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Dosing guidelines for GABITRIL have been established only for its use as an adjunctive treatment for partial seizures
and not for any other condition
GABITRIL Offers Convenient Dosing With Easy-to-Swallow Tablets1,2
The following dosing recommendations apply to all patients taking GABITRIL:
- GABITRIL is given orally and should be taken with food
- Do not use a loading dose of GABITRIL
- Dose titration: Rapid escalation and/or large dose increments of GABITRIL should not be used
- Missed dose(s): If the patient forgets to take the prescribed dose of GABITRIL at the scheduled time,
the patient should not attempt to make up for the missed dose by increasing the next dose. If a patient has
missed multiple doses, patient should refer back to his or her physician for possible re-titration as clinically indicated.
- Dosage adjustment of GABITRIL should be considered whenever a change in patient's enzyme-inducing status occurs as a result
of the addition, discontinuation, or dose change of the enzyme-inducing agent
GABITRIL Offers a Favorable Pharmacokinetic Profile1,3
- Linear pharmacokinetics offer predictable systemic exposure
- Rapid absorption with peak plasma levels occurring approximately 45 minutes after dosing in a fasting state
- GABITRIL pharmacokinetics are linear (2-24 mg single dose)
GABITRIL is only indicated as adjunctive therapy in adults and children 12 years and older in the treatment of partial
seizures. Cephalon, Inc. does not recommend the use of GABITRIL for any other indication.
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